Um… Yeah. It probably would interfere with the instruments you play.

Umm it might be hard to play an instrument because it will get in the way of blowing into the instrument.

It would probably interfere with your playing.
At my school, lots of people play brass instruments with braces, and that irritates thier mouth for the first couple of weeks. It would be different if you went into playing those instruments with a piercing, but getting one in the middle of playing might be a little challenge.
Also, I don’t know if the piercing would get infected easier.

WELL I THINK U WILL NOT BE ABLE TO PLAY AN INSTRUMENT FOR A WHILE B/C UR LIPS ARE GOING TO BE SULLEN SPECIALLY IF U DO SNAKEBITE BUT LATER ON LIKE IN A MONTH IN A1/2 U WILL…..

you probably can, but you will have to take it out when you play… and considering the fact that you have to let your lip get used to the pierce (when you take it out and the hole wont close up) do it over the summer, or when ever you have a long period of time you aren’t playing an instrument.

Might be really hard!
So dont do

im pretty sure this would make it alot harder to play you’re instrument so if you still want to play i wouldnt do it

if you have an actual lip ring that might cause some difficulty because it will most likely create a space between the mouthpiece and your lip so the air you blow would go downward instead of into the instrument. what you could do to kind of test it out is take a captive bead ring (they are only about 50 cents), remove the bead, and put the part where the hole is over your lip to sort of simulate what it would be like trying to play with the piercing in.
if it turns out that it is too hard to play with it in, maybe you could consider a labret piercing and wear a stud when you are playing.

it would effect your playing majorly.